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Science. 2017 Feb 17;355(6326):710-714. doi: 10.1126/science.aai7919. Epub 2017 Jan 12.

A paralogous decoy protects Phytophthora sojae apoplastic effector PsXEG1 from a host inhibitor.

Ma Z1,2, Zhu L1,2, Song T1,2, Wang Y1,2, Zhang Q1,2, Xia Y1,2, Qiu M1,2, Lin Y1,2, Li H1,2, Kong L1,2, Fang Y3, Ye W1,2, Wang Y1,2, Dong S1,2, Zheng X1,2, Tyler BM3, Wang Y4,2.

Author information

1
Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.
2
Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.
3
Center for Genome Research and Biocomputing and Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331, USA.
4
Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China. wangyc@njau.edu.cn.

Abstract

The extracellular space (apoplast) of plant tissue represents a critical battleground between plants and attacking microbes. Here we show that a pathogen-secreted apoplastic xyloglucan-specific endoglucanase, PsXEG1, is a focus of this struggle in the Phytophthora sojae-soybean interaction. We show that soybean produces an apoplastic glucanase inhibitor protein, GmGIP1, that binds to PsXEG1 to block its contribution to virulence. P. sojae, however, secretes a paralogous PsXEG1-like protein, PsXLP1, that has lost enzyme activity but binds to GmGIP1 more tightly than does PsXEG1, thus freeing PsXEG1 to support P. sojae infection. The gene pair encoding PsXEG1 and PsXLP1 is conserved in many Phytophthora species, and the P. parasitica orthologs PpXEG1 and PpXLP1 have similar functions. Thus, this apoplastic decoy strategy may be widely used in Phytophthora pathosystems.

PMID:
28082413
DOI:
10.1126/science.aai7919
[Indexed for MEDLINE]

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