Format

Send to

Choose Destination
Chemistry. 2017 Feb 3;23(8):1860-1868. doi: 10.1002/chem.201604500. Epub 2017 Jan 3.

Quinoline-Derived Two-Photon Sensitive Quadrupolar Probes.

Author information

1
Laboratoire de Chimie et Biochimie, Pharmacologiques et Toxicologiques, Université Paris Descartes, 45, rue des Saints-Pères, 75270, Paris Cedex 06, France.
2
Univ. Bordeaux, ISM (CNRS UMR5255), Bâtiment A12, 351, Cours de la Libération, 33405, Talence Cedex, France.
3
Laboratoire de Physiologie Cérébrale, Université Paris Descartes, 45, rue des Saints-Pères, 75270, Paris Cedex 06, France.

Abstract

Quadrupolar probes derived from 8-dimethylamino-quinoline (8-DMAQ) having a pegylated fluorene core were prepared and studied under "one-photon" (λ=365 nm) and "two-photon" (TP) (λ=730 nm) irradiation conditions. Compound 1 a was identified as the most efficient probe by UV activation that showed sequential release of acetic acid as a model. Although the probe showed high two-photon absorption it stayed inert under femtosecond irradiation conditions. Fast and selective photolysis was observed, however, by using picosecond irradiation conditions with a remarkably high TP uncaging cross-section (δu =2.3 GM).

KEYWORDS:

absorption; chromophores; nonlinear optics; quinolines

PMID:
28052481
DOI:
10.1002/chem.201604500

Supplemental Content

Loading ...
Support Center