Format

Send to

Choose Destination
Int J Mol Sci. 2016 Dec 30;18(1). pii: E70. doi: 10.3390/ijms18010070.

Brain Vascular Imaging Techniques.

Author information

1
Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, 75185 Uppsala, Sweden. barbara.lavina-siemsen@igp.uu.se.

Abstract

Recent major improvements in a number of imaging techniques now allow for the study of the brain in ways that could not be considered previously. Researchers today have well-developed tools to specifically examine the dynamic nature of the blood vessels in the brain during development and adulthood; as well as to observe the vascular responses in disease situations in vivo. This review offers a concise summary and brief historical reference of different imaging techniques and how these tools can be applied to study the brain vasculature and the blood-brain barrier integrity in both healthy and disease states. Moreover, it offers an overview on available transgenic animal models to study vascular biology and a description of useful online brain atlases.

KEYWORDS:

animal models; brain atlas; brain vascular disorders; computed tomography (CT); imaging; magnetic resonance angiography (MRA); magnetic resonance angiography (MRI); molecular imaging; photoacoustic imaging (PAI); positron emission tomography (PET); vascular biology

PMID:
28042833
PMCID:
PMC5297705
DOI:
10.3390/ijms18010070
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Multidisciplinary Digital Publishing Institute (MDPI) Icon for PubMed Central
Loading ...
Support Center