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Allergy. 2017 Jun;72(6):842-848. doi: 10.1111/all.13115. Epub 2017 Jan 19.

Shellfish allergens: tropomyosin and beyond.

Author information

1
Department of Immunology - Allergology - Rheumatology, Faculty of Medicine and Health Science, University of Antwerp and Antwerp University Hospital, Wilrijk, Belgium.
2
Immunology Department, Centre de Diagnòstic Biomèdic (CDB), Hospital Clínic, Universitat de Barcelona and Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
3
Department of Pediatrics, Faculty of Medicine and Health Science, University of Antwerp and Antwerp University Hospital, Wilrijk, Belgium.

Abstract

IgE-mediated shellfish allergy constitutes an important cause of food-related adverse reactions. Shellfish are classified into mollusks and crustaceans, the latter belonging to the class of arthropoda. Among crustaceans, shrimps are the most predominant cause of allergic reactions and thus more extensively studied. Several major and minor allergens have been identified and cloned. Among them, invertebrate tropomyosin, arginine kinase, myosin light chain, sarcoplasmic calcium-binding protein, and hemocyanin are the most relevant. This review summarizes our current knowledge about these allergens.

KEYWORDS:

Allergens; cross-reactivity; crustaceans; mollusks; shrimp

PMID:
28027402
DOI:
10.1111/all.13115
[Indexed for MEDLINE]

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