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J Clin Hypertens (Greenwich). 2017 May;19(5):550-557. doi: 10.1111/jch.12960. Epub 2016 Dec 26.

A prospective study of the association between total sleep duration and incident hypertension.

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Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju, South Korea.
Department of Cardiology, Yonsei University Wonju College of Medicine, Wonju, South Korea.


The aim of this prospective study was to evaluate total sleep duration as a potential risk factor for the development of hypertension after a mean of 2.6 years of follow-up. The study participants comprised 1715 Korean adults aged 40 to 70 years. The participants were without hypertension at baseline (2005-2008) and during follow-up (2008-2011) to determine the incident cases of hypertension. Based on a self-reported questionnaire, the individuals were stratified according to total sleep duration (<6 hours, 6-7.9 hours, 8-9.9 hours, ≥10 hours). Hypertension was defined according to the Eighth Joint National Committee (JNC 8) guidelines. After an average of 2.6 years of follow-up, 164 (9.56%) participants developed hypertension. In multivariate adjusted models, the odds ratio for new-onset hypertension was 1.71 (95% confidence interval, 1.01-2.89) in participants with a short sleep duration (<6 hours) compared with those who reported 6 to 7.9 hours of sleep. Long sleep duration (more than 8 hours) did not have any significant difference on incident hypertension. Among middle-aged and elderly Korean adults, short sleepers were independently associated with a higher risk of developing hypertension.


Korean adults; hypertension; prospective study; sleep duration

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