Extinction Coefficient of Gold Nanostars

J Phys Chem C Nanomater Interfaces. 2015 Jul 30;119(30):17408-17415. doi: 10.1021/acs.jpcc.5b03624. Epub 2015 Jul 15.

Abstract

Gold nanostars (NStars) are highly attractive for biological applications due to their surface chemistry, facile synthesis and optical properties. Here, we synthesize NStars in HEPES buffer at different HEPES/Au ratios, producing NStars of different sizes and shapes, and therefore varying optical properties. We measure the extinction coefficient of the synthesized NStars at their maximum surface plasmon resonances (SPR), which range from 5.7 × 108 to 26.8 × 108 M-1cm-1. Measured values correlate with those obtained from theoretical models of the NStars using the discrete dipole approximation (DDA), which we use to simulate the extinction spectra of the nanostars. Finally, because NStars are typically used in biological applications, we conjugate DNA and antibodies to the NStars and calculate the footprint of the bound biomolecules.

Keywords: DDA; DDSCAT; Gold nanostar; HEPES; discrete dipole approximation; molar extinction coefficient; multibranched gold nanoparticle; nanoflower; optical properties.