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Trends Neurosci. 2017 Mar;40(3):127-128. doi: 10.1016/j.tins.2016.12.001. Epub 2016 Dec 22.

Neuronal Adaptation: Tired Neurons or Wired Networks?

Author information

1
Department of Neurobiology, Duke University, Durham, NC, USA. Electronic address: mayo@neuro.duke.edu.
2
Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: matt@smithlab.net.

Abstract

Neuronal adaptation - time-dependent modulation of sensory responses following sequential stimuli - is thought to be a consequence of synaptic plasticity. But recent, empirically-grounded, modeling by Quiroga and colleagues demonstrates that the adaptation of visual cortical responses can be described by recurrent network connections with fixed synaptic weights.

KEYWORDS:

Adaptation; cortex; modeling; plasticity; recurrent dynamics; vision

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PMID:
28017499
DOI:
10.1016/j.tins.2016.12.001
[Indexed for MEDLINE]

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