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Urology. 2017 Jun;104:11-21. doi: 10.1016/j.urology.2016.12.011. Epub 2016 Dec 19.

Prostate Biopsy-related Infection: A Systematic Review of Risk Factors, Prevention Strategies, and Management Approaches.

Author information

1
School of Medicine, The University of Queensland, Brisbane, QLD, Australia; Centre for Clinical Research, The University of Queensland, Brisbane, QLD, Australia; Department of Urology, Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia. Electronic address: m.roberts2@uq.edu.au.
2
School of Medicine, The University of Queensland, Brisbane, QLD, Australia.
3
School of Medicine, The University of Queensland, Brisbane, QLD, Australia; Centre for Clinical Research, The University of Queensland, Brisbane, QLD, Australia; Pathology Queensland, Department of Microbiology, Central Laboratory, Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia.
4
Urology Department, Waikato Hospital, Hamilton, New Zealand.
5
Department of Urology, Alfred Health, Melbourne, VIC, Australia; Department of Surgery, Monash University, Melbourne, VIC, Australia.
6
Department of Urology, Technical University of Munich, Munich, Germany.
7
Clinic for Urology, Pediatric Urology and Andrology, Justus Liebig University Giessen, Giessen, Germany.

Abstract

A systematic review to identify risk factors for prostate biopsy-related infection, preventative strategies, and optimal management of infectious complications was conducted. Significant risk factors for postbiopsy infection include urogenital infection, antibiotic use, international travel, hospital exposure, bacteriuria, previous transrectal biopsy, and resistance of fecal flora to antibiotic prophylaxis (especially fluoroquinolones). Patients at risk may benefit from an adjusted biopsy protocol comprising transrectal biopsy under targeted prophylaxis, and/or the use of rectal disinfection techniques or using a transperineal approach. Management of biopsy-related infection should be based on individual risk and local resistance profiles with input from multiple specialties.

PMID:
28007492
DOI:
10.1016/j.urology.2016.12.011
[Indexed for MEDLINE]

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