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Semin Musculoskelet Radiol. 2016 Nov;20(5):472-485. doi: 10.1055/s-0036-1594281. Epub 2016 Dec 21.

Percutaneous Ablation in Painful Bone Tumors.

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Department of Radiology, Musculoskeletal Division, University of Southern California, Los Angeles, California.
Mallinckrodt Institute of Radiology, Neuroradiology Section, Washington University School of Medicine, Saint Louis, Missouri.
Mallinckrodt Institute of Radiology, Musculoskeletal Section, Washington University School of Medicine, Saint Louis, Missouri.


Percutaneous image-guided ablation has been shown to be safe and effective for the treatment of benign osseous lesions and has evolved into the treatment of metastatic lesions for both pain palliation and local tumor control. Ablation is increasingly becoming part of the treatment algorithm of painful bone lesions, requiring multidisciplinary input from radiation, surgical, and medical oncologists. Substantial pain reduction is often possible in those who have failed to benefit from conventional therapies such as systemic and radiation therapy. This review details the basics of bone ablation including indications, treatment algorithms, ablation modalities, role of imaging, thermo-protective techniques, and the emerging use for local tumor control in patients with oligometastatic disease.

[Indexed for MEDLINE]

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