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Mol Cell. 2016 Dec 15;64(6):1013-1015. doi: 10.1016/j.molcel.2016.11.037.

Come Together: CRISPR-Cas Immunity Senses the Quorum.

Author information

1
Waksman Institute for Microbiology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
2
Waksman Institute for Microbiology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA; Skolkovo Institute of Science and Technology, 143026 Skolkovo, Russia. Electronic address: severik@waksman.rutgers.edu.

Abstract

In this issue of Molecular Cell, Patterson et al. (2016) reveal a functional link between the CRISPR-Cas and quorum sensing systems, which could allow bacteria to activate the potentially lethal adaptive immunity when they need it most: in high-density cultures, when bacteriophage infections can be most detrimental.

PMID:
27984739
DOI:
10.1016/j.molcel.2016.11.037
[Indexed for MEDLINE]
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