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Curr Pharm Des. 2017;23(4):565-573. doi: 10.2174/1381612822666161216122230.

Endophthalmitis Prophylaxis in Cataract Surgery: Overview of Current Practice Patterns Around the World.

Author information

1
Professor of Ophthalmology, Department of Ophthalmology Poznan City Hospital, Ul. Szwajcarska 3, 60- 285, Poznan. Poland.
2
Department of Ophthalmology, University of Warmia and Mazury, Olsztyn. Poland.
3
Department of Ophthalmology, Nojima Hospital, Tottori. Japan.
4
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON. United States.
5
Division of Ophthalmology, McMaster University, Hamilton, ON. Canada.
6
Eye and Vision Epidemiology Research Group, The University of Western Australia Perth. Australia.
7
Department of Ophthalmology, University of Auckland. New Zealand.
8
Department of Ophthalmology, Beijing Tongren Hospital Eye Center, Capital Medical University Beijing. China.
9
Dr. Agarwal's Eye Hospital, Chennai. India.
10
Department of Ophthalmology, Oregon Health & Science University, Portland, Oregon. United States.
11
Klinik Meta Nusantara, Jakarta. Indonesia.
12
Visionmed Eye and Laser Clinic, Johannesburg. South Africa.
13
S. Fyodorov Eye Microsurgery State Institution, Moscow. Russian Federation.
14
Department of Ophthalmology, University Clinic Reina Fabiola, Catholic University of Cordoba. Argentina.
15
Argentine Council of Ophthalmology, Buenos Aires. Argentina.
16
Department of Ophthalmology, Santa Lucia Hospital, University of Buenos Aires. Argentina.
17
Instituto de Oftalmologia Fundacion Conde de Valenciana, Mexico City. Mexico.
18
School of Medicine, Tecnologico de Monterrey, Nuevo Leon. Mexico.
19
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL. United States.
20
Aravind Eye Hospital, Madurai. India.
21
Umea University, Umea. Sweden.

Abstract

BACKGROUND:

Acute-onset postoperative endophthalmitis after cataract surgery remains a rare but important cause of visual loss. There is no global consensus regarding the optimal strategies for prophylaxis of endophthalmitis and practices vary substantially around the world, especially with respect to the use of intracameral antibiotics. The European Society of Cataract & Refractive Surgeons in a randomized clinical trial (2007) reported an approximately 5-fold reduction in endophthalmitis rates associated with the use of intracameral cefuroxime. Despite this report, the use of intracameral antibiotics has not been universally adopted.

METHODS:

Various endophthalmitis prophylaxis patterns around the world (including the United States, Canada, Australia/New Zealand, Japan, China, India, Indonesia, South Africa, Argentina, Russia, Sweden and Mexico) are compared. Each contributing author was asked to provide similar information, including endophthalmitis rates based on published studies, current practice patterns, and in some cases original survey data. Various methods were used to obtain this information, including literature reviews, expert commentary, and some new survey data not previously published.

RESULTS:

Many different practice patterns were reported from around the world, specifically with respect to the use of intracameral antibiotics.

CONCLUSION:

There is no worldwide consensus regarding endophthalmitis prophylaxis with cataract surgery.

KEYWORDS:

Endophthalmitis; cataract surgery; cataract surgery complications; endophthalmitis prophylaxis; intracameral antibiotics; topical antibiotics

[Indexed for MEDLINE]

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