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Nature. 1989 Oct 12;341(6242):508-13.

A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched.

Author information

1
ICRF Developmental Biology Unit, Department of Zoology, Oxford, UK.

Abstract

The patterning of cells in insect segments requires the exchange of information between cells, which in Drosophila depends on the activity of members of the segment-polarity class of genes. Here we report the molecular characterization of one such gene, patched. We find that patched encodes a large protein with several possible membrane-spanning domains and is expressed in a complex pattern during embryogenesis.

PMID:
2797178
DOI:
10.1038/341508a0
[Indexed for MEDLINE]

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