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Best Pract Res Clin Rheumatol. 2016 Oct;30(5):802-825. doi: 10.1016/j.berh.2016.10.007. Epub 2016 Nov 9.

The eye and inflammatory rheumatic diseases: The eye and rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis.

Author information

1
Academic Unit of Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Birmingham and Midland Eye Centre, Birmingham B18 7QU, UK. Electronic address: p.i.murray@bham.ac.uk.
2
Academic Unit of Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Birmingham and Midland Eye Centre, Birmingham B18 7QU, UK.

Abstract

Rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis are associated with potentially sight-threatening inflammatory eye disease. Although the ocular manifestations associated with ankylosing spondylitis and psoriatic arthritis are similar, such as anterior uveitis, this differs from rheumatoid arthritis where dry eye, peripheral ulcerative keratitis and scleritis are the major ocular complications. Apart from causing sight loss, these conditions are painful, debilitating, often recurrent or chronic and may require long-term therapy. Treatments such as ocular lubricant, topical corticosteroid, systemic corticosteroid and systemic immunosuppression are often similar for the underlying systemic disease. Yet for the treatment of the ocular complications, the evidence base is weak. Close collaboration with a rheumatologist is often essential, particularly in the management of these patients.

KEYWORDS:

Anterior uveitis; Dry eye; Peripheral ulcerative keratitis; Scleritis

PMID:
27964790
DOI:
10.1016/j.berh.2016.10.007
[Indexed for MEDLINE]

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