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J Periodontol. 2017 Apr;88(4):348-356. doi: 10.1902/jop.2016.160471. Epub 2016 Dec 13.

Effect of a Connective Tissue Graft in Combination With a Single Flap Approach in the Regenerative Treatment of Intraosseous Defects [Formula: see text].

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Research Center for the Study of Periodontal and Peri-Implant Diseases, University of Ferrara, Ferrara, Italy.
Operative Unit of Dentistry, University-Hospital, Ferrara, Italy.
Institute for Inpatient Treatment and Scientific Studies Foundation, Ca' Granda Polyclinic, Milan, Italy.



In the attempt to limit the post-surgery increase in buccal gingival recession (bREC), effect of a connective tissue graft (CTG) when combined with a buccal single flap approach (SFA) in the regenerative treatment of intraosseous defects is evaluated.


Data related to 30 patients with an intraosseous defect treated with a buccal SFA with (SFA+CTG group; n = 15) or without (SFA group; n = 15) placement of a CTG and regenerative treatment were retrospectively derived at three clinical centers. bREC and probing parameters were assessed at presurgery and 6 months post-surgery.


In addition to a significant attachment gain and probing depth reduction, adjunctive use of a CTG to a buccal SFA in the regenerative treatment of periodontal intraosseous defects associated with a buccal bone dehiscence resulted in a limited post-surgery bREC, a lower prevalence of defects with a clinically detectable apical displacement of the gingival margin, and an increase in gingival width and thickness.


Adjunctive use of a CTG in the regenerative treatment of intraosseous defects associated with buccal bone dehiscence accessed by buccal SFA may support the stability of the gingival profile.


Alveolar bone loss; enamel matrix proteins; gingival recession; periodontitis; reconstructive surgical procedures; surgical flaps

[Indexed for MEDLINE]

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