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Clin Med (Lond). 2016 Dec;16(Suppl 6):s53-s59.

Multiple sclerosis, a treatable disease.

Author information

1
University College London, London, UK anisha.doshi@ucl.ac.uk.
2
University College London, London, UK.

Abstract

This article reviews our current understanding and modern treatment of multiple sclerosis (MS). MS is a disabling condition resulting in devastating social and economic impacts. As MS can affect any part of the central nervous system, the presentation is often diverse; however, there are key features that can be useful in the clinic. We comment on the diagnostic criteria and review the main subtypes of MS, including clinically isolated syndrome, relapsing remitting MS, secondary progressive MS and primary progressive MS. Although the underlying aetiology of MS is still not known, we summarise those with most evidence of association. Finally, we aim to present treatment strategies for managing the acute relapse, disease-modifying therapies and MS symptoms. This review highlights that progressive MS is an area where there is currently a paucity of available disease-modifying treatments and this will be a major focus for future development.

KEYWORDS:

Diagnostic criteria; epidemiology; multiple sclerosis; progressive multiple sclerosis; treatments

PMID:
27956442
PMCID:
PMC6329568
DOI:
10.7861/clinmedicine.16-6-s53
[Indexed for MEDLINE]
Free PMC Article

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