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  • PMID: 27940943 was deleted because it is a duplicate of PMID: 28172581
Clin Infect Dis. 2017 Feb 15;64(4):459-467. doi: 10.1093/cid/ciw804.

First Occurrence of Diabetes, Chronic Kidney Disease, and Hypertension Among North American HIV-Infected Adults, 2000-2013.

Author information

1
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
2
Centers for Disease Control and Prevention, Atlanta, Georgia.
3
Veterans Affairs Connecticut Healthcare System, West Haven.
4
Mid-Atlantic Permanente Research Institute, Kaiser Permanente Mid-Atlantic States, Rockville, Maryland.
5
University of Calgary, Alberta, Canada.
6
Vanderbilt University, Nashville, Tennessee.
7
Kaiser Permanente Division of Research, Kaiser Permanente Northern California, Oakland.
8
Northwestern University, Chicago, Illinois.
9
University of Washington, Seattle.
10
British Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada.
11
University of North Carolina at Chapel Hill.
12
Harvard School of Public Health, Boston, Massachusetts.
13
Universidad Central del Caribe, Bayamon, Puerto Rico.

Abstract

Background:

There remains concern regarding the occurrence of noncommunicable diseases (NCDs) among individuals aging with human immunodeficiency virus (HIV), but few studies have described whether disparities between demographic subgroups are present among individuals on antiretroviral therapy (ART) with access to care.

Methods:

We assessed the first documented occurrence of type 2 diabetes mellitus (DM), chronic kidney disease (CKD), and treated hypertension (HTN) by age, sex, and race within the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). HIV-infected adults (≥18 years) who initiated ART were observed for first NCD occurrence between 1 January 2000 and 31 December 2013. Cumulative incidences as of age 70 were estimated accounting for the competing risk of death; Poisson regression was used to compare rates of NCD occurrence by demographic subgroup.

Results:

We included >50000 persons with >250000 person-years of follow-up. Median follow-up was 4.7 (interquartile range, 2.4–8.1) years. Rates of first occurrence (per 100 person-years) were 1.2 for DM, 0.6 for CKD, and 2.6 for HTN. Relative to non-black women, the cumulative incidences were increased in black women (68% vs 51% for HTN, 52% vs 41% for DM, and 38% vs 35% for CKD; all P < .001); this disparity was also found among men (73% vs 60% for HTN, 44% vs 34% for DM, and 30% vs 25% for CKD; all P < .001).

Conclusions:

Racial disparities in the occurrence of DM, CKD, and HTN emphasize the need for prevention and treatment options for these HIV populations receiving care in North America.

PMID:
28172581
PMCID:
PMC5850614
DOI:
10.1093/cid/ciw804
[Indexed for MEDLINE]

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