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Dig Dis Sci. 2017 Feb;62(2):502-509. doi: 10.1007/s10620-016-4389-6. Epub 2016 Dec 8.

Telephone-Based Mindfulness Therapy Intervention for Patients with Chronic Pancreatitis.

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Department of Medicine, Stanford Hospital, Stanford, CA, USA.
Division of Gastroenterology, Stanford Hospital, Stanford, CA, USA.
Division of Gastroenterology, University of Washington Medical Center, Seattle, WA, USA.
Division of Gastroenterology, University of Massachusetts, Worcester, MA, USA.
Center for Integrative Medicine, Stanford School of Medicine, Stanford, CA, USA.
Department of Medicine, Stanford Hospital, Stanford, CA, USA.



Patients with chronic pancreatitis (CP) have substantially impaired quality of life (QOL) both physically and mentally. Mindfulness therapy is a form of treatment that has been shown to be beneficial in many medical conditions but has not been evaluated in the CP patient population.


The aims of this study were (1) to test the feasibility and usability of a novel telephone-based mindfulness therapy service for patients with CP and (2) to determine whether there was any effect on CP quality of life.


We recruited ten patients with suspected or confirmed CP and five controls who were asked to utilize our telephone-based mindfulness therapy service daily for 28 days. Feasibility of the service was defined as the fraction of subjects with a ≥50% compliance rate. Usability was assessed using a System Usability Scale (SUS). QOL was evaluated using the SF-36 questionnaire and the Pancreatitis Quality of Life Instrument (PANQOLI). Paired t tests were used to compare the SF-36 and PANQOLI pre- and post-intervention.


There was an overall compliance rate of 67%. The mean SUS score for all participants was 79.3, above the average published score of 68. Results showed a significant improvement in the SF-36 Mental Component Summary scores after 28 days of mindfulness therapy for patients with CP, t(9) = 2.48, p = 0.035. There was also a significant improvement in the mean total PANQOLI scores in CP patients, t(9) = 2.41, p = 0.04, most notably in the social domain.


Our telephone-based mindfulness therapy service represents a feasible and easily usable treatment adjunct for patients with CP, which may provide benefit in QOL by improving mental health-related domains.


Chronic pancreatitis; Mindfulness therapy; Mobile application; Quality of life

[Indexed for MEDLINE]

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