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World J Gastrointest Surg. 2016 Nov 27;8(11):761-765.

Treatment options for spontaneous and postoperative sclerosing mesenteritis.

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Jennifer Klasen, Department of Surgery, Kantonsspital Frauenfeld, Spital Thurgau AG, CH-8500 Frauenfeld, Switzerland.


Sclerosing mesenteritis is a rare pathology with only a few described cases in the literature. The etiology is unclear; however, several potential triggers, including abdominal surgery and abdominal trauma, have been discussed. The pathology includes a benign acute or chronic inflammatory process affecting the adipose tissue of the mesenterium. Despite it being a rare disease, sclerosing mesenteritis is an important differential diagnosis in patients after abdominal surgery or patients presenting spontaneously with signs of acute inflammation and abdominal pain. We present here three cases with sclerosing mesenteritis. In two cases, sclerosing mesenteritis occurred postoperatively after abdominal surgery. One patient was treated because of abdominal pain and specific radiological signs revealing spontaneous manifestation of sclerosing mesenteritis. So far there are no distinct treatment algorithms, so the patients were treated differently, including steroids, antibiotics and watchful waiting. In addition, we reviewed the current literature on treatment options for this rare disease.


Abdominal pain; Immunosuppression; Inflammation; Sclerosing mesenteritis; Surgery

Conflict of interest statement

Conflict-of-interest statement: All authors have no conflicts of interest or financial ties to disclose.

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