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Cell Stem Cell. 2016 Dec 1;19(6):673-674. doi: 10.1016/j.stem.2016.11.013.

Fetal to Adult Hematopoiesis with the "Flk" of a Switch.

Author information

1
Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, 223 62 Lund, Sweden.
2
Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, 223 62 Lund, Sweden. Electronic address: joan.yuan@med.lu.se.

Abstract

Blood development relies on discrete stem and progenitor cell populations with unclear lineage relationships and distinct functional characteristics that change during ontogeny. In this issue of Cell Stem Cell, Beaudin et al. (2016) identify a hematopoietic stem cell population with fetal characteristics that is developmentally restricted yet capable of long-term multi-lineage reconstitution upon transplantation into adult recipients.

PMID:
27912084
DOI:
10.1016/j.stem.2016.11.013
[Indexed for MEDLINE]
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