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Biochem Soc Trans. 2016 Oct 15;44(5):1549-1560.

Can the Drosophila model help in paving the way for translational medicine in heart failure?

Author information

1
Bournemouth University, Bournemouth, U.K.

Abstract

Chronic heart failure is a common consequence of various heart diseases. Mechanical force is known to play a key role in heart failure development through regulating cardiomyocyte hypertrophy. In order to understand the complex disease mechanism, this article discussed a multi-disciplinary approach that may aid the illustration of heart failure molecular process.

KEYWORDS:

Drosophila melanogaster; heart failure; integrins; mechanical forces; mechanotransduction

PMID:
27911738
DOI:
10.1042/BST20160017C
[Indexed for MEDLINE]
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