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Vestn Oftalmol. 2016;132(5):81-85. doi: 10.17116/oftalma2016132581-85.

[. Oсumethyl in the treatment of allergic diseases of eyelids and conjunctiva].

[Article in Russian; Abstract available in Russian from the publisher]

Author information

1
Research Institute of Eye Diseases, 11 A,B, Rossolimo St., 119021 Moscow, Russian Federation.

Abstract

in English, Russian, Russian

Treatment of allergic diseases of eyelids and conjunctiva (conjunctivites and blepharoconjunctivites) often presents difficulties due to peculiarities of their pathogenesis - allergic and vascular reactions, disorder of lacrimal production, meibomian gland dysfunction, and possible bacterial contamination. It has been suggested to use Ocumethyl, which contains zinc sulfate (binding, drying, anti-inflammatory, and antiseptic effect), diphenhydamine hydrochloride (an Н1-antihistamine that decreases capillary permeability and helps resolve conjunctival and eyelid edema), naphazoline hydrochloride (a sympathomimetic notable for its strong, rapid, and long-lasting vasoconstrictive effect), and methylene blue (antiseptic effect, disintoxication, and antioxidant activity). A total of 80 patients with chronic allergic conjunctivitis, blepharoconjuntivitis, or giant papillary conjunctivitis associated with contact lens wearing were treated with Ocumethyl instillations (3 times daily for 15-30 days). A clinically significant effect was obtained in 77-91% of patients depending on the disease entity.

PMID:
27911431
[Indexed for MEDLINE]

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