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Emerg Med Clin North Am. 2017 Feb;35(1):219-231. doi: 10.1016/j.emc.2016.09.006.

The Past, Present, and Future of the Centers for Medicare and Medicaid Services Quality Measure SEP-1: The Early Management Bundle for Severe Sepsis/Septic Shock.

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Department of Emergency Medicine, Brigham and Women's Hospital, Harvard Medical School, 10 Vining Street, Boston, MA 02115, USA. Electronic address:
Division of Emergency Critical Care, Department of Emergency Medicine, Stony Brook Hospital, 101 Nicolls Road, Stony Brook, NY 11704, USA.


SEP-1, the new national quality measure on sepsis, resulted from an undertaking to standardize care for severe sepsis and septic shock regardless of the size of the emergency department where the patient is being treated. SEP-1 does not necessarily follow the best current evidence available. Nevertheless, a thorough understanding of SEP-1 is crucial because all hospitals and emergency providers will be accountable for meeting the requirements of this measure. SEP-1 is the first national quality measure on early management of sepsis care. This article provides a review of SEP-1 and all its potential implications on sepsis care in the United States.


CMS; Core measures; Early goal-directed therapy; Quality; Sepsis; Septic shock; Severe sepsis; Shared decision-making

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