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Cancer Genet Cytogenet. 1989 Oct 15;42(2):243-51.

Isochromosome 12p in mediastinal germ cell tumor.

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1
Centre for Human Genetics, University of Leuven, Belgium.

Abstract

The occurrence of an i(12p) in an extragonadal mediastinal germ cell tumor indicates that this chromosome change, which is characteristic for testicular germ cell tumors, can also occur in germ cell tumors present elsewhere in the body. In addition, the karyotype in this patient was near-diploid, in contrast with testicular germ cell tumors, which as a rule are near-triploid or near-tetraploid.

PMID:
2790759
[Indexed for MEDLINE]
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