Send to

Choose Destination
Nucleic Acids Res. 2017 Jan 4;45(D1):D758-D768. doi: 10.1093/nar/gkw1116. Epub 2016 Nov 28.

The Zebrafish Model Organism Database: new support for human disease models, mutation details, gene expression phenotypes and searching.

Author information

The Institute of Neuroscience, University of Oregon, Eugene, OR 97403-1254, USA
The Institute of Neuroscience, University of Oregon, Eugene, OR 97403-1254, USA.


The Zebrafish Model Organism Database (ZFIN; is the central resource for zebrafish (Danio rerio) genetic, genomic, phenotypic and developmental data. ZFIN curators provide expert manual curation and integration of comprehensive data involving zebrafish genes, mutants, transgenic constructs and lines, phenotypes, genotypes, gene expressions, morpholinos, TALENs, CRISPRs, antibodies, anatomical structures, models of human disease and publications. We integrate curated, directly submitted, and collaboratively generated data, making these available to zebrafish research community. Among the vertebrate model organisms, zebrafish are superbly suited for rapid generation of sequence-targeted mutant lines, characterization of phenotypes including gene expression patterns, and generation of human disease models. The recent rapid adoption of zebrafish as human disease models is making management of these data particularly important to both the research and clinical communities. Here, we describe recent enhancements to ZFIN including use of the zebrafish experimental conditions ontology, 'Fish' records in the ZFIN database, support for gene expression phenotypes, models of human disease, mutation details at the DNA, RNA and protein levels, and updates to the ZFIN single box search.

[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Silverchair Information Systems Icon for PubMed Central
Loading ...
Support Center