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Mult Scler. 2017 Oct;23(11):1554-1557. doi: 10.1177/1352458516679894. Epub 2016 Nov 29.

Hispanic Americans and African Americans with multiple sclerosis have more severe disease course than Caucasian Americans.

Author information

1
Department of Neurology, School of Medicine, New York University, New York, NY, USA/Ambulatory Care Center, NYU Langone Medical Center, New York, NY, USA.
2
Neuromedical Clinic of Central Louisiana, Alexandria, LA, USA.
3
Department of Neurology, School of Medicine, New York University, New York, NY, USA.
4
Department of Neurology, School of Medicine, New York University, New York, NY, USA/Barnabas Multiple Sclerosis Care Center, RWJBarnabas Health, Livingston, NJ, USA.

Abstract

Whether disease course in Hispanic Americans (HA) with multiple sclerosis (MS) is different from Caucasian Americans (CA) or African Americans (AA) is unknown. We compared MS severity in the three main ethnic populations in our tertiary MS clinics using disease duration-adjusted rank score of disability: Patient-Derived Multiple Sclerosis Severity Score (P-MSSS). The age- and gender-adjusted P-MSSS was significantly higher in HA (3.9 ± 2.6) and AA (4.5 ± 3.0) compared to CA (3.4 ± 2.6; p < 0.0001 for both). Adjusting for insurance did not change these results. These findings suggest that HA, as AA, have more rapid disability accumulation than CA.

KEYWORDS:

African American; Caucasian; Hispanic; Multiple sclerosis; disease severity; ethnicity

PMID:
27899551
DOI:
10.1177/1352458516679894
[Indexed for MEDLINE]

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