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Cureus. 2016 Oct 15;8(10):e831.

Focal Seizures Induced by Intracranial Electroencephalogram Grids.

Author information

Department of Neurosurgery, The Hospital of the University of Pennsylvania.
Department of Neurology, University of Colorado Hospital.
Department of Neurology, The Hospital of the University of Pennsylvania.


Here we present a unique, but important seizure variant directly related to placement of subdural grids. Two distinct epileptogenic zones were identified, one which correlated with the patient's baseline seizures and a separate zone associated with atypical semiology and localization. Inspection of this zone at surgery revealed cortical deformation from the grid itself. The patient underwent successful surgical resection of the primary epileptogenic zone, but not that of the atypical zone. She remains seizure free at two years following surgery. Recognition of grid-induced seizures is important as they may confound the interpretation of intracranial electroencephalograms (iEEG) and mislead resective surgery.


eeg analysis; epilepsy surgery; refractory epilepsy; seizures

Conflict of interest statement

The authors have declared that no competing interests exist.

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