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Int J Immunopathol Pharmacol. 2016 Dec;29(4):595-602. Epub 2016 Oct 6.

Sudden sensorineural hearing loss: Is there a connection with inner ear electrolytic disorders? A literature review.

Author information

1
ENT & Audiology Department University Hospital of Ferrara, Italy.
2
World Hearing Center, Warsaw, Poland.
3
Institute of Physiology and Pathology of Hearing, Warsaw, Poland.
4
Department of Heart Failure and Cardiac Rehabilitation, Medical University of Warsaw, Warsaw, Poland.
5
Institute of Sensory Organs, Kajetany, Poland.
6
ENT & Audiology Department University Hospital of Ferrara, Italy sdh1@unife.it.

Abstract

Electrolytic disorders of the inner ear represent a model that could be implicated in partially explaining the pathogenesis of sudden sensorineural hearing loss (SSNHL). Different types of electrolytes and different inner-ear loci are involved in cochlear homeostasis physiologically, to ensure the maintenance of an ion-balanced cochlear environment allowing a normal hair cell function. It has been hypothesized that a sudden loss of endocochlear potential, due to a rapid disruption of the inner ear fluid osmolality, could be responsible for a deterioration of the hearing function caused by damaged hair cells. The aim of this paper was to review the current literature and identify sources which might validate/fortify the hypothesis that inner ear electrolytic disorders have a role in the etiopathogenesis of SSNHL. The data in the literature underline the importance of ionic homeostasis in the inner ear, but they do not support a direct link between SSNHL and electrolyte disorders/imbalances. There is marginal evidence from otoacoustic emissions research that an indirect link might be present.

KEYWORDS:

cochlea; electrolytes; inner ear; sudden sensorineural hearing loss

PMID:
27895287
PMCID:
PMC5806825
DOI:
10.1177/0394632016673845
[Indexed for MEDLINE]
Free PMC Article

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