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J Dermatol Sci. 2017 Jun;86(3):181-186. doi: 10.1016/j.jdermsci.2016.11.006. Epub 2016 Nov 15.

Stem cells in psoriasis.

Author information

1
Institute of Dermatology, Taiyuan City Central Hospital, Shanxi Key Laboratory for Immunological Dermatosis, No. 1 Dong San Dao Xiang, Taiyuan, Shanxi, 030009, China.
2
Institute of Dermatology, Taiyuan City Central Hospital, Shanxi Key Laboratory for Immunological Dermatosis, No. 1 Dong San Dao Xiang, Taiyuan, Shanxi, 030009, China. Electronic address: zhangkaiming@sina.com.

Abstract

Psoriasis is a complex chronic relapsing inflammatory disease. Although the exact mechanism remains unknown, it is commonly accepted that the development of psoriasis is a result of multi-system interactions among the epidermis, dermis, blood vessels, immune system, neuroendocrine system, metabolic system, and hematopoietic system. Many cell types have been confirmed to participate in the pathogenesis of psoriasis. Here, we review the stem cell abnormalities related to psoriasis that have been investigated recently.

KEYWORDS:

Mesenchymal stem cells; Psoriasis; Stem cells

PMID:
27894778
DOI:
10.1016/j.jdermsci.2016.11.006
[Indexed for MEDLINE]

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