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Surg Oncol Clin N Am. 2017 Jan;26(1):143-161. doi: 10.1016/j.soc.2016.07.009.

Uncommon Anal Neoplasms.

Author information

1
Department of Medical Oncology, Flinders Centre for Innovation in Cancer, Flinders Medical Centre, Flinders Drive Bedford Park, South Australia, 5042 Australia; Department of Surgery, Flinders University, Sturt Road, Bedford Park, South Australia 5042, Australia.
2
Department of Surgery, Flinders University, Sturt Road, Bedford Park, South Australia 5042, Australia; Department of Surgery, Flinders Medical Centre, Flinders Drive Bedford Park, South Australia, 5042, Australia.
3
Department of Surgery, Flinders University, Sturt Road, Bedford Park, South Australia 5042, Australia; Department of Anatomical Pathology, SA Pathology (Flinders Medical Centre), Flinders Drive Bedford Park, South Australia 5042, Australia.
4
Division of Medical Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada Toronto, Ontario, Canada; Department of Medicine, Medical Sciences Building, 1 King's College Cir #3172, University of Toronto, Toronto, ON M5S 1A8, Canada.
5
Department of Radiation Oncology, St Vincent's Hospital, Victoria Street, Darlinghurst, Sydney, 2010 New South Wales, Australia.
6
Department of Radiology, Dr Jones & Partners Medical Imaging, Tennyson Centre, 520 South Road, Kurralta Park South Australia 5037, Australia.
7
Department of Medicine, St Vincent's Clinical School, St Vincent's Hospital, University of New South Wales, Level 5 de Lacy, 438 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia. Electronic address: e.segelov@unsw.edu.au.

Abstract

Uncommon neoplasms of the anal canal are associated with significant diagnostic dilemma in clinical practice and a high index of suspicion and pathologic expertise is needed. The incidence is likely to increase, particularly of small, incidental lesions found because of use of more frequent colonoscopy and high-definition MRI. Generally treatment follows that of the same histologic subtype in other anatomic location. Surgical intervention is the cornerstone for cure in early/localized disease; however, removal of the anal canal is associated with significant morbidities and quality of life issues. A centralized global registry/database established under the auspices of the International Rare Care Initiative collaboration would be useful.

KEYWORDS:

Anal lymphoma; Anal melanoma; Anal neuroendocrine tumor; Unusual cancers

PMID:
27889033
DOI:
10.1016/j.soc.2016.07.009
[Indexed for MEDLINE]

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