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Facial Plast Surg Clin North Am. 2017 Feb;25(1):89-97. doi: 10.1016/j.fsc.2016.08.008.

Treating Scars on the Oral Mucosa.

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Division of Oral and Maxillofacial Surgery, University of Cincinnati Medical Center, Veterans Affairs Medical Center, Cincinnati Children's Hospital Medical Center, 200 Albert Sabin Way, ML 0461, Cincinnati, OH 45219, USA. Electronic address:


Mucosal wounds tend to heal more rapidly than skin wounds and with minimal to no scar formation and hence have a minimal impact on function or aesthetics. This is likely due to differences in the magnitude and timing of the various factors that contribute to wound healing. Some examples of these differences are fibroblast proliferation, transforming growth factor-β, macrophages, neutrophils, and T cells. Other factors, such as the moist environment, contribute to the favorable wound-healing characteristics of mucosa.


Epithelium; Fibroblast; Mucosa; Scar; Skin; TGF-β; Wound

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