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Catheter Cardiovasc Interv. 2017 May;89(6):1051-1058. doi: 10.1002/ccd.26878. Epub 2016 Nov 26.

Initial clinical experience with the Medtronic Micro Vascular Plug™ in transcatheter occlusion of PDAs in extremely premature infants.

Author information

1
Division of Pediatric Cardiology, Department of Pediatrics, University of Tennessee Health Science Center, LeBonheur Children's Hospital, Memphis, Tennessee.
2
Division of Pediatric Cardiology, Department of Pediatrics, The Lillie Frank Abercrombie Section of Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
3
Division of Pediatric Cardiology, Department of Pediatrics, A.I. Dupont Hospital For Children, Wilmington, Delaware.

Abstract

OBJECTIVES:

To describe the early multicenter, clinical experience with the Medtronic Micro Vascular Plug™ (MVP) for the occlusion of patent ductus arteriosus (PDA) in premature infants.

BACKGROUND:

The MVP is a large diameter plug that can be delivered through a microcatheter for occlusion of abnormal blood vessels.

METHODS:

A Retrospective review of PDA embolization procedures performed in two centers using the MVP was performed.

RESULTS:

Fifteen premature infants underwent attempted PDA occlusion using the MVP. The gestational age and birth weight were 25.6 ± 2.5 weeks and 735 ± 251 g, respectively. The median weight and age at the time of the procedure were 1,210 g (700-3,500 g) and 4.5 weeks (2-12 weeks), respectively. Median procedure and fluoroscopy times were 45 and 6.5 min, respectively. The median radiation and contrast doses were 19.7 mGy and 2.4 mL/kg, respectively. Antegrade occlusion was successfully achieved in 13 patients <2 kg with only femoral venous access aided by echo guidance. The two patients >2 kg had arterial access and attempted retrograde occlusion; one of which was unsuccessful due to the PDA being short and wide. Complete closure was observed in 13 of 14 successful procedures (93%), with one patient having a small residual shunt that was not seen on follow-up. There were no complications related to the procedure or noted during follow-up (Median 11 months).

CONCLUSIONS:

The MVP is a new, large-diameter vascular embolization device that may be useful for the occlusion of PDA in extremely small, premature infants. © 2016 Wiley Periodicals, Inc.

KEYWORDS:

Micro Vascular Plug™; patent ductus arteriosus; premature

PMID:
27888552
DOI:
10.1002/ccd.26878
[Indexed for MEDLINE]

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