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J Am Acad Dermatol. 2017 Mar;76(3):464-471. doi: 10.1016/j.jaad.2016.09.034. Epub 2016 Nov 22.

Development and validation of a patient-reported outcome measure in vitiligo: The Self Assessment Vitiligo Extent Score (SA-VES).

Author information

1
Department of Dermatology, Ghent University Hospital, Ghent, France. Electronic address: Nanja.vangeel@UGent.be.
2
Department of Dermatology, University of Amsterdam and Netherlands Institute for Pigment Disorders, Amsterdam, The Netherlands.
3
VU University Medical Center, Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, Amsterdam, The Netherlands.
4
Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, United Kingdom.
5
National Reference Center for Rare Skin Diseases, Hôpital St-André, University Hospital Center of Bordeaux, Bordeaux, France.
6
San Gallicano Dermatology Institute, Via Elio Chianesi, Roma, Italy.
7
EA EpiDermE (Epidémiologie en Dermatologie et Evaluation des Thérapeutiques), UPE-Université Paris-Est, Service de Dermatologie, Hôpital Henri Mondor, Paris, France.
8
Department of Dermatology, Ghent University Hospital, Ghent, France.

Abstract

BACKGROUND:

The Vitiligo Extent Score (VES) has recently been introduced as a physicians' score for the clinical assessment of the extent of vitiligo, but a good patient self-assessment score is lacking.

OBJECTIVE:

The objective is to develop and validate a simplified version of the VES as a patient-reported outcome measure (PROM).

METHODS:

After extensive pilot testing, patients were asked to score their vitiligo extent twice with an interval of 2 weeks using the Self Assessment Vitiligo Extent Score (SA-VES). The scores were compared with the physicians' evaluation (VES).

RESULTS:

The SA-VES demonstrated very good test-retest reliability (intraclass correlation = 0.948, 95% confidence interval [CI]: 0.911-0.970) that was not affected by age, skin type, or vitiligo distribution pattern. According to patients, this evaluation method was easy to use (22% very easy; 49% easy; 29% normal) and required <5 minutes in the majority of patients (73%, <5 minutes; 24%, 5-10 minutes; 2%, 10-15 minutes). Comparison of the SA-VES and the VES demonstrated excellent correlation (r = 0.986, P <.001).

LIMITATIONS:

Few patients had a dark skin type.

CONCLUSION:

The results demonstrate excellent reliability of the SA-VES and excellent correlation with its investigator-reported counterpart (VES). This patient-oriented evaluation method provides a useful tool for the assessment of vitiligo extent.

KEYWORDS:

body surface area; outcome measurement; patient-reported outcomes; severity; vitiligo

PMID:
27887798
DOI:
10.1016/j.jaad.2016.09.034
[Indexed for MEDLINE]

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