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Clin Geriatr Med. 2017 Feb;33(1):17-26. doi: 10.1016/j.cger.2016.08.002.

Pathogenesis and Management of Sarcopenia.

Author information

1
National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, 9000 Rockville Pike, Building 10, Room Number 3-2340, Bethesda, MD 20892, USA.
2
National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, 9000 Rockville Pike, Building 10, Room Number 3-2340, Bethesda, MD 20892, USA. Electronic address: hasnisa@mail.nih.gov.

Abstract

Sarcopenia represents a loss of muscle strength and mass in older individuals. Sarcopenia in the elderly has now become a major focus of research and public policy debate due to its impact on morbidity, mortality, and health care expenditure. Despite its clinical importance, sarcopenia remains under-recognized and poorly managed in routine clinical practice. This is, in part, due to a lack of available diagnostic testing and uniform diagnostic criteria. The management of sarcopenia is primarily focused on physical therapy for muscle strengthening and gait training. There are no pharmacologic agents for the treatment of sarcopenia.

KEYWORDS:

Aging; Fall risk; Frailty; Muscle atrophy; Muscle strength; Sarcopenia; Senescence; Skeletal muscle mass loss

PMID:
27886695
PMCID:
PMC5127276
DOI:
10.1016/j.cger.2016.08.002
[Indexed for MEDLINE]
Free PMC Article

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