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AIDS Res Hum Retroviruses. 1989 Aug;5(4):431-40.

A general model for the transmembrane proteins of HIV and other retroviruses.

Author information

1
Department of Microbiology, Immunology and Parasitology, Louisiana State University Medical Center, New Orleans 70112.

Abstract

A hypothetical model of the transmembrane (TM) protein of human immunodeficiency virus (HIV) is proposed that is derived from the known structure of the influenza TM protein HA2. This model is consistent with computer algorithms of predicted protein structure and with known properties of TM proteins determined by sequence homology, site-directed mutations, peptide analogs, immunochemistry, or other biologic means. It is applicable to a wide variety of retroviral TM proteins differing widely in overall molecular weight.

PMID:
2788443
DOI:
10.1089/aid.1989.5.431
[Indexed for MEDLINE]

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