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Pak J Med Sci. 2016 Sep-Oct;32(5):1263-1267.

Comparison of parameters of bone profile and homocysteine in physically active and non-active postmenopausal females.

Author information

1
Dr. Sundus Tariq, MBBS, M.Phil. Assistant Professor of Physiology, University Medical & Dental College, Faisalabad-38000, Pakistan.
2
Dr. Khalid Parvez Lone, M.Sc., M.I. Biol., Ph.D., F.Z.S.P. Prof. & Head of Department of Physiology/Metabolic Disorders, University of Health Sciences, Lahore, Pakistan.
3
Dr. Saba Tariq, MBBS, M.Phil. Assistant Professor of Pharmacology, University Medical & Dental College, Faisalabad-38000, Pakistan.

Abstract

BACKGROUND AND OBJECTIVES:

Optimal physical activity is important in attaining a peak bone mass. Physically active women have better bone mineral density and reduce fracture risk as compared to females living a sedentary life. The objective of this study was to compare parameters of bone profile and serum homocysteine levels in physically active and non-active postmenopausal females.

METHODS:

In this cross sectional study postmenopausal females between 50-70 years of age were recruited and divided into two groups: Physically inactive (n=133) performing light physical activity and Physically active (n=34) performing moderate physical activity. Physical activity (in metabolic equivalents), bone mineral density and serum homocysteine levels were assessed. Spearman's rho correlation was applied to observe correlations. Two independent sample t test and Mann Whitney U test were applied to compare groups. P-value ≤ 0.05 was taken statistically significant.

RESULTS:

Parameters of bone profile were significantly higher and serum homocysteine levels were significantly lower in postmenopausal females performing moderate physical activity as compared to females performing light physical activity. Homocysteine was not significantly related to T-score and Z-score in both groups.

CONCLUSION:

Improving physical activity could be beneficial for improving the quality of bone, decreasing fracture risk and decreasing serum homocysteine levels.

KEYWORDS:

Bone Mineral Density; Homocysteine; Osteoporosis; Physical activity

Conflict of interest statement

Declaration of interest: The authors have no conflict of interest.

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