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World J Gastrointest Pharmacol Ther. 2016 Nov 6;7(4):503-512.

Logical hypothesis: Low FODMAP diet to prevent diverticulitis.

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Yoshiharu Uno, Office Uno Column (Medical Science Publisher), Onoe-Cho, Hyogo 675-0025, Japan.


Despite little evidence for the therapeutic benefits of a high-fiber diet for diverticulitis, it is commonly recommended as part of the clinical management. The ongoing uncertainty of the cause(s) of diverticulitis confounds attempts to determine the validity of this therapy. However, the features of a high-fiber diet represent a logical contradiction for colon diverticulitis. Considering that Bernoulli's principle, by which enlarged diameter of the lumen leads to increased pressure and decreased fluid velocity, might contribute to development of the diverticulum. Thus, theoretically, prevention of high pressure in the colon would be important and adoption of a low FODMAP diet (consisting of fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) may help prevent recurrence of diverticulitis.


Bernoulli’s principle; Diverticular disease; High-fiber diet; Irritable bowel syndrome; Low FODMAP diet

Conflict of interest statement

Conflict-of-interest statement: Uno Y was granted a trademark of low FODMAP diet from the Japan Patent Office. van Velkinburgh JC declares no conflicts of interest in relation to the publication of this review.

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