miRNA-Coordinated Networks as Promising Therapeutic Targets for Acute Kidney Injury

Anton Jan van Zonneveld; Ton J Rabelink; Roel Bijkerk

doi:10.1016/j.ajpath.2016.10.017

miRNA-Coordinated Networks as Promising Therapeutic Targets for Acute Kidney Injury

Am J Pathol. 2017 Jan;187(1):20-24. doi: 10.1016/j.ajpath.2016.10.017. Epub 2016 Nov 17.

Authors

Anton Jan van Zonneveld¹, Ton J Rabelink¹, Roel Bijkerk²

Affiliations

¹ Einthoven Laboratory for Experimental Vascular Medicine, Department of Internal Medicine (Nephrology), Leiden University Medical Center, Leiden, the Netherlands.
² Einthoven Laboratory for Experimental Vascular Medicine, Department of Internal Medicine (Nephrology), Leiden University Medical Center, Leiden, the Netherlands. Electronic address: r.bijkerk@lumc.nl.

PMID: 27865759
DOI: 10.1016/j.ajpath.2016.10.017

Abstract

This commentary highlights the article by Wilflingseder et al that investigates the relationship between in vivo inhibition of miR-182 by antisense oligonucleotides and improved post-injury kidney function.

Publication types

Review

MeSH terms

Acute Kidney Injury / genetics*
Acute Kidney Injury / therapy*
Animals
Cell Cycle / genetics
Gene Regulatory Networks*
Humans
MicroRNAs / genetics
MicroRNAs / metabolism*
Molecular Targeted Therapy*
Signal Transduction / genetics

Substances

MicroRNAs