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J Atten Disord. 2016 Nov 18. pii: 1087054716679262. [Epub ahead of print]

Dyskinesia in Treatment-Naive and Stimulant-Treated Children With ADHD.

Author information

1
Semmelweis University, Budapest, Hungary kereszteny.agnes@ppk.elte.hu.
2
Eötvös Loránd University, Budapest, Hungary.
3
Vadaskert Child Psychiatry Hospital, Budapest, Hungary.
4
Institute of Psychology, Eötvös Loránd University, School of PhD Budapest, Hungary.

Abstract

OBJECTIVE:

Stimulants are safe and effective medications for the treatment of ADHD. There are a number of case studies that report stimulant-induced dyskinesia. The aim of this study was to compare dyskinesia in a treated and a treatment-naive group of children with ADHD, and a healthy control group.

METHOD:

Children aged 6 to 18 years were involved in the study (n = 158). Diagnosis of ADHD was measured with the Mini International Neuropsychiatric Interview Kid (MINI Kid). Dyskinesia was assessed with the Abnormal Involuntary Movement Scale (AIMS).

RESULTS:

Before methylphenidate administration, the treated ADHD group showed significantly higher AIMS total score than the control group (p = .001) and the treatment-naive ADHD group (p < .001). We found the same pattern 1.5 hr after methylphenidate administration.

CONCLUSION:

These results call attention that clinicians should take special care for the possible development of dyskinesia during the treatment of their ADHD patients with methylphenidate.

KEYWORDS:

ADHD; children; methylphenidate; stimulants

PMID:
27864427
DOI:
10.1177/1087054716679262

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