Format

Send to

Choose Destination
Bull Cancer. 2016 Nov;103(11S):S243-S247. doi: 10.1016/j.bulcan.2016.09.005. Epub 2016 Nov 14.

[Polymorphism in HLA and KIR genes and the impact on hematopoietic stem cell transplantation outcomes and unrelated donor selection: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].

[Article in French]

Author information

1
EFS Rhône Alpes, laboratoire HLA, 1 et 3, rue du Vercors, 69007 Lyon, France.
2
AP-HP, hôpital Saint-Louis, Aphérèse thérapeutique, 1, rue Claude-Vellefaux, 75010 Paris, France.
3
CHU de Lille, laboratoire HLA, boulevard Pr-Jules-Leclerc, 59037 Lille cedex, France.
4
EFS Pays de la Loire, laboratoire HLA et EA4271, 34, boulevard Jean-Monnet, 44011 Nantes, France.
5
CHU de Nancy Brabois, laboratoire HLA, rue du Morvan, 54500 Vandoeuvre-les-Nancy, France.
6
Hôpital Robert-Debré, laboratoire d'immunologie, 48, boulevard Serurier, 75019 Paris, France.
7
EFS Alpes-Méditerranée, laboratoire HLA, 149, boulevard Baille, 13005 Marseille, France.
8
CHU Estaing, hématologie clinique et thérapie cellulaire, 58, rue Montalembert, 63000 Clermont-Ferrand, France.
9
EFS Île-de-France, laboratoire HLA ILP, 1, voie Felix-Eboue, 94010 Créteil, France.
10
CHU de Lille, université Lille 2, LIRIC Inserm U995, 59000 Lille, France. Electronic address: sfgm-tc@orange.fr.
11
AP-HP, hôpital Saint-Louis, laboratoire Jean-Dausset, 1, rue Claude-Vellefaux, 75010 Paris, France.

Abstract

In an attempt to harmonize clinical practices among French hematopoietic stem cell transplantation centers, the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) held its sixth annual workshop series in September 2015 in Lille. This event brought together practitioners from across the country with the purpose of offering careful analysis of published studies on clinical practice issues that remain to be disputed. This article addresses the impact of HLA and KIR gene polymorphism on the outcome of the transplantation in order to optimize unrelated donor selection.

KEYWORDS:

Greffe de CSH; Gènes HLA; Gènes KIR; HLA genes; HSCT; Incompatibilités permissives/non permissives; KIR genes; Overall survival; Permissive/non permissive incompatibilities; Survie globale

PMID:
27855950
DOI:
10.1016/j.bulcan.2016.09.005
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center