Send to

Choose Destination
Eur J Prev Cardiol. 2017 Feb;24(3):257-264. doi: 10.1177/2047487316679527. Epub 2016 Nov 16.

Multicomponent cardiac rehabilitation in patients after transcatheter aortic valve implantation: Predictors of functional and psychocognitive recovery.

Author information

1 Centre of Rehabilitation Research, University of Potsdam, Germany.
2 Cardiological Outpatient Clinic Am Park Sanssouci, Potsdam, Germany.
3 MediClin Rehabilitation Centre Spreewald, Burg, Germany.
4 Sana Heart-Centre Cottbus, Cottbus, Germany.
5 Brandenburgklinik Berlin-Brandenburg, Bernau, Germany.
6 Heart Centre Brandenburg, Bernau, Germany.
7 Department of Medical Biometry and Epidemiology, University Medical Centre, Hamburg-Eppendorf, Germany.
8 Klinik am See, Rehabilitation Centre for Internal Medicine, Rüdersdorf, Germany.


Background In the last decade, transcatheter aortic valve implantation has become a promising treatment modality for patients with aortic stenosis and a high surgical risk. Little is known about influencing factors of function and quality of life during multicomponent cardiac rehabilitation. Methods From October 2013 to July 2015, patients with elective transcatheter aortic valve implantation and a subsequent inpatient cardiac rehabilitation were enrolled in the prospective cohort multicentre study. Frailty-Index (including cognition, nutrition, autonomy and mobility), Short Form-12 (SF-12), six-minute walk distance (6MWD) and maximum work load in bicycle ergometry were performed at admission and discharge of cardiac rehabilitation. The relation between patient characteristics and improvements in 6MWD, maximum work load or SF-12 scales were studied univariately and multivariately using regression models. Results One hundred and thirty-six patients (80.6 ± 5.0 years, 47.8% male) were enrolled. 6MWD and maximum work load increased by 56.3 ± 65.3 m ( p < 0.001) and 8.0 ± 14.9 watts ( p < 0.001), respectively. An improvement in SF-12 (physical 2.5 ± 8.7, p = 0.001, mental 3.4 ± 10.2, p = 0.003) could be observed. In multivariate analysis, age and higher education were significantly associated with a reduced 6MWD, whereas cognition and obesity showed a positive predictive value. Higher cognition, nutrition and autonomy positively influenced the physical scale of SF-12. Additionally, the baseline values of SF-12 had an inverse impact on the change during cardiac rehabilitation. Conclusions Cardiac rehabilitation can improve functional capacity as well as quality of life and reduce frailty in patients after transcatheter aortic valve implantation. An individually tailored therapy with special consideration of cognition and nutrition is needed to maintain autonomy and empower octogenarians in coping with challenges of everyday life.


Cardiac rehabilitation; TAVI; exercise capacity; frailty; quality of life

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center