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Investig Clin Urol. 2016 Nov;57(6):424-430. Epub 2016 Nov 1.

Nationwide incidence and treatment pattern of benign prostatic hyperplasia in Korea.

Author information

1
Department of Urology, Seoul National University Hospital, Seoul, Korea.
2
Department of Urology, Dongguk University Ilsan Medical Center, Goyang, Korea.
3
Department of Urology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.
4
Department of Urology, Samsung Medical Center, Seoul, Korea.
5
Department of Urology, Inje University Busan Paik Hospital, Busan, Korea.
6
Department of Urology, Eulji General Hospital, Seoul, Korea.

Abstract

PURPOSE:

To investigate the incidence of benign prostatic hyperplasia (BPH) in Korea and treatment patterns for 3 years after the diagnosis in a nationwide database.

MATERIALS AND METHODS:

We created a cohort of patients diagnosed of BPH between 2007 and 2011 from the Health Insurance Review & Assessment database, a nationwide database of reimbursement. The diagnosis of BPH was defined as having the diagnosis of BPH (N40.0 in International Classification of Diseases, 10th revision) as a primary or secondary diagnosis ≥2 times in 2008. The incidence of BPH in 2008 was calculated. Treatment patterns were determined in 3 months interval and traced for 3 years. The incidence and timing of surgery were also determined. For patients taking medications preoperatively, medication-free rate was calculated.

RESULTS:

The incidence of BPH was 2,105 per 100,000 men (mean age, 59.7±11.4 years), and increased with age. Surgery was performed for 7,955 patients (2.1%), half of the surgery being performed within the first 6 months. Transurethral resection of the prostate was the most commonly performed surgery. The proportion of treatment increased with age until the 7th decade of life. The patients taking medication for >1 year after the initial diagnosis was 21.4%. On average, 82% of patients became medication-free at postoperative 1 year. For patients taking preoperative anticholinergics, 1 year medication-free rate was 73.3%.

CONCLUSIONS:

The incidence of BPH increased with age. Surgery was performed in 2.1% of patients. More than 4/5 patients discontinued medication after surgery, while patients taking preoperative anticholinergics were less likely to.

KEYWORDS:

Epidemiology; Lower urinary tract symptoms; Prostatic hyperplasia; Time-to-treatment

PMID:
27847916
PMCID:
PMC5109794
DOI:
10.4111/icu.2016.57.6.424
[Indexed for MEDLINE]
Free PMC Article

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