Send to

Choose Destination
See comment in PubMed Commons below
Biochem Biophys Res Commun. 1989 Sep 15;163(2):1032-7.

L-arginine is a precursor for nitrate biosynthesis in humans.

Author information

  • 1Division of Toxicology, Whitaker College, Cambridge, Massachusetts 02139.


Nitrogen from L-arginine was incorporated into urinary nitrate in human subjects. Two subjects given an oral dose of [15N2]L-arginine excreted 24 and 17 umol [15N]nitrate/24 hr, respectively, in their urine in the 24 hr period following the dose. This work demonstrates that L-arginine, a nitrogen source for biosynthesized nitrate in cultured cells and research animals, is a precursor for endogenously synthesized nitrate in humans.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center