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Arch Ophthalmol. 1989 Sep;107(9):1312-5.

Superior segmental optic hypoplasia. A sign of maternal diabetes.

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Department of Neurological Surgery, School of Medicine, University of California, San Francisco 94143.


In a review of 10 patients with superior segmental optic nerve hypoplasia, all of whom were the children of diabetic mothers, 17 of 20 eyes had one or more of four characteristic findings in the optic disc: relative superior entrance of the central retinal artery, pallor of the superior disc, superior peripapillary halo, and thinning of the superior peripapillary nerve fiber layer. We believe that the presence of these four signs of superior segmental optic nerve hypoplasia strongly suggests maternal diabetes.

[Indexed for MEDLINE]

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