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J Cell Biol. 2016 Nov 7;215(3):305-307.

A microtubule dynamics reconstitutional convention.

Author information

1
Department of Biology, University of North Carolina, Chapel Hill, NC 27599 kslep@bio.unc.edu.

Abstract

In vitro reconstitution is the fundamental test for identification of the core components of a biological process. In this issue, Moriwaki and Goshima (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201604118) reconstitute all phases of microtubule dynamics through the inclusion of five key regulators and demonstrate that Polo kinase activity shifts the system from an interphase mode into an enhanced mitotic mode.

PMID:
27821492
PMCID:
PMC5100300
DOI:
10.1083/jcb.201610066
[Indexed for MEDLINE]
Free PMC Article

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