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Acta Otolaryngol. 2017 May;137(5):541-545. doi: 10.1080/00016489.2016.1249945. Epub 2016 Nov 4.

Clinical outcome and health-related quality-of-life following microsurgical reconstruction in patients with oral and oropharyngeal cancer.

Author information

1
a Department of Otorhinolaryngology, Head and Neck Surgery, and Audiology, Rigshospitalet , Copenhagen University Hospital , Copenhagen , Denmark.
2
b Department of Plastic Surgery, Breast Surgery, and Burns Treatment, Rigshospitalet , Copenhagen University Hospital , Copenhagen , Denmark.
3
c Department of Otorhinolaryngology, Head and Neck Surgery, and Audiology, Rigshospitalet , Copenhagen University Hospital , Copenhagen , Denmark.

Abstract

CONCLUSION:

Radial forearm free flap (RFFF) and fibula free flap (FFF) provide high safety and reliability with low incidence of free flap failure and an acceptable level of complications and health-related quality-of-life (HRQoL).

OBJECTIVES:

To determine the clinical outcomes and long-term HRQoL in patients with oral or oropharyngeal cancer following free flap reconstruction.

METHODS:

A retrospective review of medical records and self-administered HRQoL questionnaires, EORTC QLQ-C30, and -H&N35. All patients who underwent surgery for oral or oropharyngeal cancer followed by primary reconstruction by RFFF or FFF at Rigshospitalet between September 2001 and November 2011 were included.

RESULTS:

The study comprised 19 patients still alive out of 61 patients. The free flap success rate was 94.7%. Early post-operative complications occurred in 11 patients (57.9%); however, only three cases (15.8%) required re-surgery. Nine patients (47.4%) developed late complications, including mandibular osteoradionecrosis in six cases (31.6%). Most patients obtained acceptable values of global quality-of-life and relatively high scores on the functional scales.

KEYWORDS:

Head and neck neoplasms; free tissue flaps; post-operative complications; quality-of-life

PMID:
27809693
DOI:
10.1080/00016489.2016.1249945
[Indexed for MEDLINE]

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