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Gynecol Endocrinol. 2017 Feb;33(2):164-167. doi: 10.1080/09513590.2016.1239254. Epub 2016 Nov 4.

Ovarian endometriosis and vitamin D serum levels.

Author information

1
a Woman's Health Sciences Department, Gynecologic Section, Polytechnic University of Marche , Ancona , Italy.

Abstract

AIM:

The aim of this study was to assess the vitamin D serum level in women with ovarian endometriosis; specifically, a possible correlation between the dimensions of ovarian endometriomas and vitamin D serum levels was evaluated.

MATERIALS AND METHODS:

This was an observational study of childbearing-age women diagnosed with singleton ovarian endometrioma from January 2015 to December 2015. Women diagnosed with multiple ovarian endometriomas or extraovarian endometriosis were excluded.

RESULTS:

Forty-nine women constituted the initial study cohort. In these women, the mean (±SD) 25-OH-D3 serum level was 22.0 (±8.9) ng/ml, and 42 of them (85.7%) were diagnosed with hypovitaminosis D. In the "hypovitaminosis D women", the mean (± SD) diameter of ovarian endometriomas was 40.2 ± 22.6 mm, while in the "normal vitamin D serum level women" it was 26.7 ± 12.1 mm (p = 0.1). However, a significant linear correlation between 25-OH-D3 serum level and the diameter of ovarian endometriomas was found (r = -0.3, p = 0.03).

CONCLUSION:

We found a relatively high rate of women with ovarian endometriosis and hypovitaminosis D. Interestingly, a significant linear correlation between 25-OH-D3 serum levels and the diameter of ovarian endometrioma emerged.

KEYWORDS:

Endometriosis; hypovitaminosis D; ovarian endometrioma; vitamin D

PMID:
27809683
DOI:
10.1080/09513590.2016.1239254
[Indexed for MEDLINE]

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