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Intern Med. 2016;55(21):3185-3190. Epub 2016 Nov 1.

Fibromyalgia in a Patient with Cushing's Disease Accompanied by Central Hypothyroidism.

Author information

1
Department of Hematology, Endocrinology and Metabolism, Niigata University Faculty of Medicine, Japan.

Abstract

A 39-year-old woman with a 3-year history of a rounded face developed widespread myalgia. Detailed examinations revealed no disorders that could explain the pain other than concomitant Cushing's disease and central hypothyroidism. Both the hypercortisolemia and hypothyroidism completely resolved after the patient underwent surgery to treat Cushing's disease, but she continued to experience unresolved myalgia and met the diagnostic criteria for fibromyalgia. Few studies have so far investigated patients with fibromyalgia associated with Cushing's syndrome. In our case, the hypothyroidism caused by Cushing's disease probably played an important role in triggering and exacerbating fibromyalgia. This highlights the need to examine the endocrine function in patients with muscle pain.

PMID:
27803417
PMCID:
PMC5140872
DOI:
10.2169/internalmedicine.55.5926
[Indexed for MEDLINE]
Free PMC Article

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