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Turk J Ophthalmol. 2015 Dec;45(6):268-270. Epub 2015 Dec 5.

Comet Lesions in Patients with Pseudoxanthoma Elasticum.

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Yeditepe University Faculty of Medicine, Department of Ophthalmology, İstanbul, Turkey.


Pseudoxanthoma elasticum (PXE) is a genetic multisystemic disorder affecting the skin, eyes and cardiovascular system. Basic fundoscopic findings in PXE result from Bruch's membrane involvement. The most important fundoscopic findings are angioid streaks. Other significant ocular findings are peau d'orange appearance, optic disc drusen, pattern dystrophy-like macular appearance, comet lesions, and choroidal neovascularization. Comet lesions are a pathognomonic ocular finding for PXE. The presence of both angioid streaks in the fundus and typical skin lesions should alert clinicians to PXE. Herein, we present two PXE cases with comet lesions.


Pseudoxanthoma elasticum; angioid streaks; comet lesions

Conflict of interest statement

No conflict of interest was declared by the authors. Financial Disclosure: The authors declared that this study received no financial support.

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