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BMJ Case Rep. 2016 Oct 20;2016. pii: bcr2016215956. doi: 10.1136/bcr-2016-215956.

Native valve Proteus mirabilis endocarditis: successful treatment of a rare entity formulated by in vitro synergy antibiotic testing.

Author information

1
Department of Medicine, University at Buffalo State University of New York, School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
2
Department of Pharmacy, Veterans Administration Western New York Healthcare System, Buffalo, New York, USA.
3
Laboratory for Antimicrobial Pharmacodynamics, University at Buffalo School of Pharmacy and Pharmaceutical Sciences, Buffalo, New York, USA.
4
State University of New York at Buffalo, Buffalo, New York, USA.
5
Veterans Administration Western New York Healthcare System, Buffalo, NY, USA.

Abstract

Infective endocarditis caused by Proteus mirabilis is a rare and poorly reported disease, with no well-defined effective antibiotic regimen. Here, we present a case of P. mirabilis aortic valve endocarditis. We reviewed prior cases and treatment regimens, and devised effective treatment, which was guided by in vitro sensitivity and synergy testing on the pathogen. Our patient survived without complications or the need for a surgical intervention.

PMID:
27797858
PMCID:
PMC5073702
DOI:
10.1136/bcr-2016-215956
[Indexed for MEDLINE]
Free PMC Article

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