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Indian J Dent. 2016 Sep;7(3):144-148.

Human immunodeficiency virus associated plasmablastic lymphoma: A case report.

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Department of Oral and Maxillofacial Pathology and Microbiology, AJ Institute of Dental Sciences, Manipal, Karnataka, India.
Post-Doctoral Fellow, Melaka Manipal Medical College, Manipal, Karnataka, India.
Department of Dentistry, Kanachur Medical Hospital and Research Centre, Deralakatte, Mangalore, Karnataka, India.


Non-Hodgkin's lymphoma (NHL) is the third common malignant lesion of the oral region. Plasmablastic lymphomas are rare, aggressive neoplasms occurring mostly in human immunodeficiency virus (HIV) infected individual which accounts for approximately 2.6% of all NHL. It usually presents as a diffuse growth and with diffuse pattern of histological presentation. It is very difficult to differentiate this lymphoma from other NHL. Immunohistochemical evaluation of various markers is an important criteria of the diagnostic protocol. Here, we describe a case of plasmablastic lymphoma in a 50-year-old female HIV-infected patient. The diagnosis was based on histopathological examination and immunophenotyping.


Human immunodeficiency virus infection; non-Hodgkin's lymphoma; plasmablastic lymphoma

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